LET Gel Use in Adults

Published: September 10, 2021

LET emergency room

Skin lacerations account for 8.2% of trips to the Emergency Department in the U.S.(1) The goals of laceration repair are to achieve hemostatic closure and avoid infection while optimizing cosmetic outcome.(2) “While topical anesthetics are frequently used in pediatric patients requiring painful procedures, their use in adults is not as prevalent.”(2)

A study reviewed the charts of 275 patients over the age of 8 who required stitches in the Emergency Department.  The study found that of the 89 patients treated with LET gel during triage, only 21 required additional anesthesia. The researchers drew on a previous study to point out that even when additional anesthesia is required (via injection), the injection is less painful when the patient is first treated with LET gel.(1) Longer lacerations and those on the extremities were more likely to require additional anesthesia than those on the head.(1)

The study concluded: “LET gel is a valuable alternative to infiltrative anesthesia for laceration repair. Its use should not be limited to children. The application of LET gel seems to be specifically suitable for short lacerations (<4 cm), lacerations located on the head, and simple finger lacerations.”(1)

For qualified providers, Edge Pharma offers LET gel in a 3mL syringe. Visit our LET gel page to easily set up an account and order.


(1) Vandamme, E. Lemoyne S., et. al., National Center for Biotechnology Information, LAT gel for Laceration Repair in the Emergency Department: Not Only for Children? https://pubmed.ncbi.nlm.nih.gov/
(2) Otterness, K., Singer, A., Clinical and Experimental Emergency Medicine, Updates in Emergency Department Laceration Management, https://www.ncbi.nlm.nih.gov/