Sterile Glycerin Perineural Injection

 

Sterile Glycerin 99% Injection 

Edge Pharma offers preservative-free sterile glycerin 99% injection packaged in a prefilled unit dose syringe. No patient names required.

 

Sterile Glycerin 99% Injection PF

Single use syringe for perineural injection 
Concentration = 99%
Syringe Volume = 2.5 mL

Refrigerate and protect from light

 

Procedure date with a minimum 2 week lead time is required. Cancellations must be received at least 72 hours prior to procedure.

Sterile glycerin injection

See Also:
Sterile Phenol 6% Injection PF

 

Review of Trigeminal Neuralgia Literature

 

Trigeminal Neuralgia, also called Tic Douloureux, is a pain condition that affects the 5th cranial nerve, or trigeminal nerve, in the head.  “The typical form of the disorder causes extreme sporadic, sudden burning or shock-like facial pain that lasts anywhere from a few seconds to as long as two minutes per episode. The intensity of the pain can be physically and mentally incapacitating.” (1) 

It is estimated that 150,000 people, most over the age of 50, are diagnosed with trigeminal neuralgia in the U.S. each year. It is more common in women than men and often runs in families. Hypertension and multiple sclerosis are risk factors. (2) 

Trigeminal neuralgia can be challenging to diagnose as other disorders that cause facial pain can have similar symptoms, such as post-herpetic neuralgia, cluster headaches, and temporomandibular joint disorder. “Most people with trigeminal neuralgia will undergo a magnetic resonance image scan to rule out a tumor or multiple sclerosis as the cause of their pain.”(1) 

The first line of treatment generally is medications to lesson or block the pain signals sent to the brain. Anticonvulsant drugs, such as carbamazepine, oxcarbazepine, and phenytoin are often prescribed. (3) 

Other treatments are percutaneous rhizotomy and/or microvascular decompression.  A study at Johns Hopkins University analyzed the outcomes of 74 patients whose treatment was the injection of glycerin into the cisternal segment of the trigeminal nerve. “Pain improvement was documented in 95.9 percent of patients.”  The study concluded, “intraoperative injection of glycerin into the trigeminal nerve is a generally safe and potentially effective treatment for trigeminal neuralgia when no distinct site of arterial compression is identified during surgery or when decompression of the nerve is deemed to be inadequate.” (4)


(1) National Institute of Neurological Disorders and Stroke online resource, Trigeminal Neuralgia Fact Sheethttps://www.ninds.nih.gov/

(2) American Association of Neurological Surgeons, online resource, Trigeminal Neuralgia https://www.aans.org/

(3) Mayo Health Clinic, online source, Trigeminal Neuralgia https://www.mayoclinic.org/

(4) Kim, T., Jackson, C., Xia, Y., Mashouf, L., Patel, K., Kim, E., Hung, A. MD, Wu, A. MD, Garzon-Muvdi, T. MD, Kim, E., Bender, M., Bettwegowda, C. MD, Lee, J. MD, Lim, M.MD, Journal of Neurosurgery, online article, Retrosigmoid Approach for Glycerin Rhizotomy in the Treatment of Trigeminal Neuralgia Without Overt Arterial Compression: Updated Case Study https://www.ncbi.nlm.nih.gov/

 

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