Edge Pharma offers Mitomycin 0.2 mg/mL and 0.4 mg/mL ophthalmic solution packaged in a pre-filled unit dose syringe.
See Also:
Mitomycin Bladder Instillation Syringes
Mitomycin Ophthalmic Solution
Concentration=0.2 or 0.4 mg/mL
Syringe Volume=0.8 mL
Literature Review
Quick – can you come up with the latitude of your address?
After you’ve looked it up, it might be interesting to consider you are much more likely to have a particular eye condition if you live between the 28th and 36th parallel, than if you live above the 40th parallel.(1)
Chronic exposure to UV light, thus the connection with a person’s proximity to the equator, is an important risk factor for pterygium, a triangle-shaped growth on the eye. The growth extends from the conjunctiva to the cornea. It gets its name from the Greek word for wing – pterygos – describing the growth’s appearance.(2) In the U.S., a pterygium is sometimes referred to as “Surfer’s Eye.” The condition is reported in medical texts dating back centuries.(3)
According to a leading health clinic, people with pterygia may not have symptoms nor need treatment. Many cases are treated with artificial tears or steroids, if there is inflammation. Surgery is indicated when the growth impairs vision, restricts eye movement, or is cosmetically bothersome.(1)
A study published in an ophthalmology journal included 60 patients undergoing surgery for pterygium. The patients were randomized with half receiving intraoperative application of mitomycin for five minutes, and the other half receiving NaCl 0.9 percent instead of the mitomycin. Patients were followed afterwards for 28 months. In the patients who were treated with mitomycin, 4 percent had a recurrence of pterygium. The patients who were not treated with mitomycin had a recurrence rate of 46.7 percent. (4)
Edge Pharma produces Mitomycin 0.2 mg/mL and 0.4 mg/mL syringes. The prefilled syringes make it easy for hospitals and surgery centers to utilize these medications.
(1) Fisher, J. MD, Medscape, Pterygium, https://emedicine.medscape.com/
(2) American Academy of Ophthalmology, online article, Pterygium – Asia Pacific, https://www.aao.org/
(3) Ento Key, Otolaryngology and Ophthalmology Insights, https://entokey.com/
(4) Frucht-Pery, J., Siganos, CS, Ilsar, M., Ophthalmology, Intraoperative Application of Topical Mitomycin C for Pterygium Surgery, https://www.sciencedirect.com/
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