Edge Pharma offers moxifloxacin ophthalmic antimicrobial injection for use by hospitals and surgery centers. It is offered in unit dose syringes.
Moxifloxacin Ophthalmic Injection
- Balanced Salt Solution
- Concentration = 1.0 mg/mL
- Syringe Volume = 0.8 mL
- Note: Formulation does not contain Xanthan Gum.
1) Haripriya, Aravind, et al. "Efficacy of Intracameral Moxifloxacin Endophthalmitis Prophylaxis at Aravind Eye Hospital." Ophthalmology 123.2 (2016): 302-308.
"Routine IC moxifloxacin prophylaxis achieved a highly significant, 4-fold reduction in postoperative endophthalmitis in patients undergoing M-SICS. Compared with previous studies, having such a high volume of patients undergoing surgery during a relatively short 14-month time period strengthens the conclusion. This study provides further evidence that moxifloxacin is an effective IC prophylactic antibiotic and suggests that IC antibiotics should be considered for M-SICS and phacoemulsification."
2) Haripriya, Aravind, David F. Chang, and Ravilla D. Ravindran. "Endophthalmitis Reduction with Intracameral Moxifloxacin Prophylaxis: Analysis of 600 000 Surgeries." Ophthalmology (2017).
"Overall, 302 815 eyes did not receive IC moxifloxacin and 314 638 eyes did, and there was a significant decline in the endophthalmitis rate, from 0.07% (214/302 815) to 0.02% (64/314 638) (P < 0.001), with moxifloxacin."
"There was also a statistical benefit for eyes complicated by PCR, and IC antibiotic prophylaxis should be strongly considered for this high-risk population."
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