Phenol Topical Solution


Podiatrists may purchase phenol as a USP grade chemical or choose to purchase Phenol 89% Topical Solution as a compounded drug product from an FDA registered and inspected 503B Outsourcing Facility. There are several advantages to securing this product from a 503B, such as Edge Pharma. First and foremost, at Edge, our Phenol 89% Topical Solution goes through rigorous testing per USP 795 and Current Good Manufacturing Practices (CGMP) requirements. This includes testing for potency and microbial enumeration. Hospitals and clinics purchasing from Edge Pharma can be assured that each batch of Phenol 89% Topical Solution is tested, prepared, and packaged according to CGMP. 

Purchasing phenol as a bulk chemical typically translates to a much larger container, which is a potential safety hazard if the container were to fall and break. Edge Pharma’s topical phenol is available in small, convenient glass bottles filled with 3mL of product, improving safety and storage.


  • Phenol Topical Solution 89%
  • 3 ml glass multi-dose vial


Qualified practitioners can buy phenol topical solution without providing patient names. Our online system makes purchasing phenol topical solution quick and easy.


phenol topical solution PF 500


Literature Review


Nail Matrixectomy and Phenol

Ingrown toenails are a common problem, affecting some 3 million people in the U.S. each year.(1) Approximately 20 percent of patients seeking foot care present with this issue.(2) While most ingrown toenails can be treated without surgery, in serious cases patients require a surgical procedure called a matrixectomy.(3)

Three stages of ingrown toenails are described. “Stage 1 is characterized by erythema, slight edema, and pain on applying pressure over the lateral nail fold. Stage 2 is marked by symptoms of Stage 1 along with infection and drainage. Stage 3 is marked by symptoms of Stage 1 along with lateral wall thickening and granulation tissue. Conservative treatment methods are used in Stage 1 ingrown toenails. Surgical treatment methods need to be considered in recurrent cases of Stage 1, Stage 2, and Stage 3 cases.”(4)

Nail matrixectomy can be performed in a number of ways – chemically, surgically, electrosurgically, or with radiofrequency ablation.(5) The most commonly used agent for chemical matrixectomy is phenol.(4) According to a medical journal for family physicians, phenol chemical ablation causes minimal bleeding, allows the patient to return to normal activities in a few days, and has a reoccurrence rate of less than 5 percent.(5) Further, “because of phenol’s antiseptic and hemostatic effects, it is particularly useful in patients with diabetes and those using anticoagulants.”(5)                           

(1) Mayo Clinic, Ingrown Toenails,
(2) Podiatry Today, Current Concepts in Performing Matrixectomies
(3) Medical News Today, What to Know About Ingrown Toenail Surgery
(4) Terzi, E. et al Indian Dermatology Online Journal, The Effectiveness of Matrix Cauterization with Trichloroacetic Acid in the Treatment of Ingrown Toenails
(5) Mayeaux, E.J. Jr. MD, Carter, C. MD, Murphy, T. MD, American Family Physician, Ingrown Toenail Management


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We are currently licensed to sell to all US states except Alabama and Virginia. To purchase Phenol topical solution please fill in the registration form. Medical, DEA, or hospital pharmacy licenses will be required.

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