BLT Topical Anesthetic Cream
BLT numbing cream is a topical anesthetic commonly used during minor cosmetic procedures, laser therapies, as a pre-injection topical, and a wide variety of other applications. As an FDA-registered 503B Outsourcing Facility, Edge Pharma is able to offer this product to dermatologists and other qualified practitioners without patient names.
BLT Compounded Topical Anesthetic Gel
Storage: room temperature, 60 gram per jar.
- Benzocaine 20%
- Lidocaine 8%
- Tetracaine 4%
Benzocaine - One of the most prevalent anesthetics used in medicine today. Benzocaine works by inhibiting voltage-dependent sodium channels on neuron membranes. It has a very fast onset and is generally well-tolerated, making it popular for a variety of applications.
Lidocaine - A commonly used topical anesthetic that was discovered in the 1940's. Lidocaine works by blocking sodium channels which, when used topically, prohibits local neurons from signaling the brain. When applied directly to the skin, Lidocaine has an onset of approximately 4 minutes.
Tetracaine - A longer acting anesthetic which works by changing the function of ryanodine receptors that control the release of intracellular calcium. Onset time is typically longer than either Benzocaine or Lidocaine when applied topically.
BLT cream can be ordered in quantities as low as a single jar for contracted customers. Volume discounts are available.
Microneedling Literature Review
Microneedling is a new treatment which is gaining popularity for the treatment of scars and for facial rejuvenation. The treatment can be performed by a dermatologist and is an office-based procedure.(1)
For the treatment, the patient’s skin is cleansed and then a topical anesthetic (numbing cream) is applied to the area being treated. A cream, composed of benzocaine, lidocaine, and tetracaine, is the topical anesthetic widely used for cosmetic procedures, including microneedling, and has been shown to provide adequate anesthesia for laser resurfacing as well.(2) An article in the Journal of Clinical and Aesthetic Dermatology underlies the importance of pain control. “Patient discomfort is an important consideration in aesthetic procedures, as is fear of needles, because it may cause anxiety in patients undergoing these treatments.”(3)
With microneedling, a dermatologist uses a dermaroller, a device with fine surgical needles, and rolls it over the skin, creating microinjuries. According to the Mayo Clinic newsletter, “as the injuries heal, the body produces capillaries, collagen and elastin that reduce fine lines, wrinkles and acne scars.” The procedure is also called collagen induction therapy (CIT) or percutaneous collagen induction (PCI).(4)
While there is a wide range of dermarollers, the standard dermaroller features a 12 cm long handle with a drum-shaped cylinder with eight rows and 192 fine microneedles ranging 0.5-3 mm in length and 0.1-0.25 mm in diameter. Several passes of the dermaroller over the skin result in approximately 250 punctures per square centimeter. The epidermis is not damaged.(5)
A study conducted at the Washington Institute of Dermatologic Laser Surgery showed positive outcomes for patients undergoing microneedling, with minimal risk of adverse effects. Of 120 patients treated for facial and nonfacial scars from a variety of sources (acne, trauma, surgery) 80 percent had 50 to 75 percent improvement and 65 percent experienced over 75 percent improvement.(6)
(1) Doddaballapur, Satish, Journal of Cutaneous and Aesthetic Surgery, online article, Microneedling with Dermaroller https://www.ncbi.nlm.nih.gov
(2) Hashim, Peter MD, Nia, John K. MD, Taliercio, Mark, Goldenberg, Gary MC, Dermatology News, online article, Local Anesthetics in Cosmetic Dermatology https://www.mdedge.com/dermatology
(3) Boonsiri, Metavee MD, Diaz, DeAnna MS, Sukmee, Theerayuth MD, Okawa, Joyce RN, Ditre, Cherie MD, Journal of Clinical and Aesthetic Dermatology, online article, Comparative Study of Compounded Aesthetic Benzocaine/Lidocaine/Tetracaine With and Without Abrasive Particles https://pubmed.ncbi.nlm.nih.gov
(4) Hicks, Patrice MD, Mayo Health Care System, online article, Skin Needling Procedure Uses Body’s Natural Healing Process https://www.mayoclinichealthsystem.org
(5) Singh, Aashim, Yadav, Savita, US National Library of Medicine, National Institutes of Health, online article, Microneedling: Advances and Widening Horizons https://www.ncbi.nlm.nih.gov
(6) Alster, Tina S. MD, Yi, Monica Ka MD, Journal of the American Society of Plastic Surgeons, online article, Microneedling of Scars: A Large Prospective Study with Long-Term Follow-Up https://journals.lww.com/plasreconsurg
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